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Adverse maternal environments perturb hepatic DNA methylome and transcriptome prior to the adult-onset non-alcoholic fatty liver disease in mouse offspring

NIAID Data Ecosystem2026-05-01 收录

非酒精性脂肪肝表观遗传学

母体环境对后代代谢编程

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE232812 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2023-08-22

非酒精性脂肪肝表观遗传学

趋化因子表达

We performed histone modification ChIP-Seq in human liver explants and showed upregulation of multiple CXCL chemokines in AH. ChIP-Seq, chromosome conformation capture assays, and in silico analysis o

NIAID Data Ecosystem70

Additional file 1 of Alterations in the hepatocyte epigenetic landscape in steatosis

非酒精性脂肪肝表观遗传学

甲基化测序

Additional file 1. Primers used for bisulfite-based PCR with subsequent SNuPE and local deep bisulfite sequencing (MiSeq). For MiSeq universal TruSeq adaptor sequences were attached to the specific se

Figshare2024-08-13 更新60

Human liver biopsy of different phases from control to NASH

非酒精性脂肪肝表观遗传学

NAFLD疾病进展分子机制

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (N=45) with all stages of NAFLD and controls

NIAID Data Ecosystem20

Methylation profiles in non-alcoholic fatty liver disease

非酒精性脂肪肝表观遗传学

肝脏疾病分子分型

Background & Aims: Cirrhosis and liver cancer are potential outcomes of advanced nonalcoholic fatty liver disease (NAFLD). It is not clear what factors determine whether patients will develop advanced

NIAID Data Ecosystem60

DNA IP for 5hmC modified CpGs in the liver of control and HFD fed mouse liver.. DNA IP for 5hmC modified CpGs in the liver of control and HFD fed mouse liver.

非酒精性脂肪肝表观遗传学

5hmC免疫沉淀测序

We carry out 5-hydroxymethylation DNA immunoprecipitation (hmeDIP) prior to sequencing Ion Proton P1 to report on the genome-wide 5hmC patterns of hepatic in murine hepatic steatosis. Overall design:

NIAID Data Ecosystem30

Adverse maternal environments perturb hepatic DNA methylome and transcriptome prior to the adult-onset non-alcoholic fatty liver disease in mouse offspring

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