Serial section TEM of touch receptor neurons from transgenic mec-12 putative null expressing mec-12 K40R

Serial section EM data with the following results. Reminiscent of the microtubule phenotype observed in mec-17;atat-2 double mutants, mec-12 null mutant TRNs expressing MEC-12(K40R) harbored polymorphic microtubules. Because this substitution replaces lysine 40 with a positively charged residue that cannot be acetylated, this finding suggests that the post- translational modification per se is crucial for the formation or stability of 15-pf microtubules.