Evaluation of Host Protein Biomarkers by ELISA from Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis

This dataset is used in the manuscript: Evaluation of Host Protein Biomarkers by ELISA from Whole Lysed Peripheral Blood for Development of Diagnostic Tests for Active Tuberculosis.In this study, we evaluate the diagnostic performance of nine biomarkers from our previously published biomarker qPCR validation; CALCOCO2, CD274, CD52, GBP1, IFIT3, IFITM3, SAMD9L, SNX10 and TMEM49, as protein moieties assayed by ELISA. This preliminary, pilot evaluation study was conducted to quantify the level of biomarker protein expression across latent, extra-pulmonary or pulmonary TB groups and negative controls, collected across the UK and India, in whole lysed blood samples (WLB).