Gating parameters of WT and mutant Kv7.1 channels.
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https://figshare.com/articles/dataset/_Gating_parameters_of_WT_and_mutant_Kv7_1_channels_/605564
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V50 (half activation voltage) and z (equivalent gating charge) were derived from fitting single Boltzmann function; I60 corresponds to the current density measured at +60 mV in pA/pF. ΔG0 and ΔΔG0c were calculated as described in methods. Data are expressed as mean ± SEM and in parentheses are indicated the number of cells.*, p<0.05 compared to WT (two-tailed, Student's unpaired t test). NA, not applicable as R231W mutant is a constitutively open K+ leak channel.
创建时间:
2013-02-21



