Observed versus expected number of significant associations, by trait and population.

The expected number of significant associations was based on power calculations assuming an additive genetic model and liberal significance threshold (0.05) in each racial/ethnic group for each test of association. We further assumed the observed genetic effect size (beta) from PAGE European Americans and the observed allele frequency, sample sizes, and trait mean/standard deviations from each non-European American population.
*Only includes associations that replicated in EA.
†Based on the additive power of all loci.
‡One-sample binomial test.
African Americans (AA); American Indians (AI); Mexican Americans/Hispanics (MA/H); number (#).