Malpighian tubules (MT) gene expression between control and yki3SA gut-tumor-bearing flies.

To investigate the function of Malpighian tubules on host wasting, we established a fly model of tumor-induced wasting by activation of an oncogene Yki in adult intestinal stem cells (ISCs) for 8 days to cause gut-tumor formation and systemic organ wasting and metabolic abnormalities. We then performed RNA-seq and gene expression analysis in Malpighian tubules from control and yki3SA tumor-bearing flies Overall design: Comparative species composition and diversity analysis, gene expression profiling analysis of meta-seq data for control and yki3SA tumor-bearing flies.