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Crystal structure of human ClpP protease in complex with TR-57

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Protein Data Bank Japan2024-05-22 更新2026-04-19 收录
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Crystal structure of human ClpP protease in complex with TR-57 Descriptor: 3-({3-[(4-chlorophenyl)methyl]-1-methyl-2,4-dioxo-1,3,4,5,7,8-hexahydropyrido[4,3-d]pyrimidin-6(2H)-yl}methyl)benzonitrile, ATP-dependent Clp protease proteolytic subunit, mitochondrial Authors: Mabanglo, M.F, Houry, W.A. Deposit date: 2022-05-02 Release date: 2023-01-11 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure, 31, 2023
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2022-05-02
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