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Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.

ChEBI2013-10-17 更新2026-07-21 收录

基因组调控

表观遗传与转录调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-1884 数据链接链接失效反馈

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资源简介：

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.

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创建时间：

2013-10-17

染色质结合

基因组调控

Satb1 (Special AT-rich sequence binding protein 1) coordinates chromatin architecture and regulates a diverse set of cellular and developmental processes. It is not yet clear how Satb1 selects it targ

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Manipulating the 3D organization of the largest synthetic yeast chromosome

合成染色体

基因组调控

Whether synthetic genomes can power life has attracted broad interest in the synthetic biology field. Here we report de novo synthesis of the largest eukaryotic chromosome thus far, synIV, a 1,454,621

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3C-seq for Mef2c. Mus musculus

发育分子机制

基因组调控

Cardiac progenitor cells hold great potential for regenerative therapies in heart disorders, however, the mechanisms regulating their expansion and differentiation remain poorly defined. Here we show

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The Myc-Associated Zinc Finger Protein (MAZ) Works Both Independently and Together with CTCF to Control Cohesin Positioning and Genome Organization

基因组调控

转录因子功能分析

Purpose: The objectives of this study are to evaluate the roles of MAZ in cellular processes using the NGS-deriveed ChIP-seq, RNA-seq and Hi-C profiles in K562 wild type and siRNA MAZ knockdown cells

NIAID Data Ecosystem50

Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes

病原体抗原变异

基因组调控

Highly selective gene expression is a key requirement for antigenic variation in several pathogens, allowing evasion of host immune responses and maintenance of persistent infections. African trypanos

NIAID Data Ecosystem20

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.

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