The 1.7A crystal structure of humanized Xenopus MDM2 with RO5045337
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The 1.7A crystal structure of humanized Xenopus MDM2 with RO5045337 Descriptor: E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]{4-[3-(methylsulfonyl)propyl]piperazin-1-yl}methanone Authors: Graves, B.J, Lukacs, C, Kammlott, R.U, Crowther, R. Deposit date: 2013-01-09 Release date: 2013-02-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models. Cancer Res., 73, 2013
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2013-01-09
