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Construction of A Human Cell Landscape by Single-cell mRNA-seq

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=24eab4b970bf5f10585f3cb5dc696eb7
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We used single-cell RNA sequencing to determine the cell type composition of all major human organs and construct a basic scheme for the human cell landscape (HCL). We reveal a single-cell hierarchy for many tissues that have not been well characterized previously. We present a “single-cell HCL analysis’’ pipeline that accurately defines human cell types and exemplify its utility in stem cell biology. Finally, we perform single-cell comparative analysis of the human and mouse cell atlases to reveal the conserved genetic networks in the mammalian system.
提供机构:
Center for Stem Cell and Regenerative Medicine
创建时间:
2022-02-20
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