Ern1

ENCODES a protein that exhibits Hsp90 protein binding; ADP binding (ortholog); ATP binding (ortholog); INVOLVED IN cellular response to glucose stimulus; cellular response to hydrogen peroxide; cellular response to manganese ion; PARTICIPATES IN endoplasmic reticulum stress - the unfolded protein response pathway; Alzheimer's disease pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Acute Lung Injury; Peritoneal Fibrosis; Subarachnoid Hemorrhage; FOUND IN AIP1-IRE1 complex (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 1,4-dithiothreitol; 17beta-estradiol

编码一种与Hsp90蛋白结合的蛋白质；参与ADP结合（同源）；ATP结合（同源）；涉及细胞对葡萄糖刺激的响应；细胞对过氧化氢的响应；细胞对锰离子的响应；参与内质网应激的未折叠蛋白反应途径；阿尔茨海默病途径；内质网相关降解途径；与急性肺损伤、腹膜纤维化、蛛网膜下腔出血相关；存在于AIP1-IRE1复合体（同源）、细胞质（同源）、内质网（同源）中；与（+）五味子素B、1,4-二硫苏糖醇、17β-雌二醇相互作用。