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Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor PJ34

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4uxb
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Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor PJ34 Descriptor: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, POLY ADP-RIBOSE POLYMERASE 1, SULFATE ION Authors: Tresaugues, L, Thorsell, A.G, Karlberg, T, Schuler, H. Deposit date: 2014-08-21 Release date: 2015-09-02 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.22 Å) Cite: Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. J. Med. Chem., 60, 2017
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2014-08-21
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