Additional file 1: of Evidence of the impact of systemic inflammation on neuroinflammation from a non-bacterial endotoxin animal model

Table S1. Analgesia measurement by von Frey filament at postoperative 24Â h. Figure S1. Activation of microglia in the brain from surgical mice. Representative confocal microphotographs presented the activation of Iba1+ microglia in the frontal cortex (M2 region, top boxes; sensory cortex, bottom boxes) and hippocampus induced by laparotomy. Figure S2. Activation of astrocyte in the frontal cortex from surgical mice. (a) Representative confocal microphotographs presented the activation of GFAP+ astrocyte in the motor cortex (M2: secondary motor cortex; AIV: agranular insular cortex, ventral part) on POD 14. (b) Representative confocal microphotographs presented the activation of GFAP+ astrocyte in the sensory cortex (aci: anterior commissure intrabulbar part; OV: olfactory ventricle (olfactory part of lateral ventricle)) induced by laparotomy on POD 14. (ZIP 27129Â kb)