10.1038/s41598-024-60145-z

Mendeley Data2026-04-09 收录

纳米药物递送

白血病靶向治疗

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raw data of "Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells and diagnostic applications" doi 10.1038/s41598-024-60145-z

Genetic and chemical targeting of the ATPase complex TIP48 and 49 impairs acute myeloid leukemia

白血病靶向治疗

ATP（三磷酸腺苷）

The chromatin-associated AAA+ ATPases Tip48 and Tip49 are the core components of various complexes implicated in diverse nuclear events such as DNA repair and gene regulation. Although they are freque

NIAID Data Ecosystem60

pH-Degradable, Bisphosphonate-Loaded Nanogels Repolarize Immunosuppressive Macrophages Towards Antifibrotic Liver Therapy

纳米药物递送

肝纤维化免疫治疗

Liver fibrosis is a hard-to-treat disease with liver transplantation as only effective curation to this date. During disease progression, immune suppressive macrophages dominate and support fibrosis f

NIAID Data Ecosystem30

Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition. Genetic or pharmacological inactivation of CREBBP sensitizes B-cell Acute Lymphoblastic Leukemia to Ferroptotic Cell Death upon BCL2 Inhibition

白血病靶向治疗

铁死亡机制

We performed a targeted drug screen in isogenic human cell lines, identifying a number of actionable small molecules that specifically target CREBBP-mutated B-ALL. The most potent was the BCL2 inhibit

NIAID Data Ecosystem20

The use of lipid sponge-like nanoparticles as carriers for macromolecules and...

纳米药物递送

大分子药物载体

Conventional ways to administer and deliver drugs have reached its limitations. These methods can be still used for small and simple molecules. However, new carriers have to be...

B2FIND40

Figure_3.jpg

纳米药物递送

体外释放动力学

In vitro release profile of eugenol encapsulated in nano-structured lipid carriers and free eugenol solution: Legend: *P<0.05 after two-way ANOVA test. NFE (Nanostructured formulation containing e

DataCite Commons2025-07-10 更新30

10.1038/s41598-024-60145-z

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