GWAS Explorer, an open-source tool to explore, visualize, and access GWAS summary statistics

GWAS explorer provides an interactive resource for genetics researchers as well as other interested individuals to search for, visualize, and download aggregated association results from DCEG genome-wide association analyses (GWAS). Initial results are posted from The Prostate, Lung, Colorectal, Ovarian (PLCO) Cancer Screening Study, a large population-based randomized trial designed and sponsored by the National Cancer Institute (NCI) to determine the effects of screening on cancer-related mortality and secondary endpoints in men and women aged 55 to 74. The screening component of the trial was completed in 2006. Cohort participants have been followed for more than two decades, resulting in a rich collection of anthropometric, lifestyle, and disease information, and includes data from several smaller-scale molecular studies. As costs for the technology have drastically decreased, the NCI Division of Cancer Epidemiology and Genetics, has genotyped 110,000 PLCO participants and by doing so created a new resource for genomic studies.