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Algorithms for detecting protein complexes in PPI networks: an evaluation study

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Research Data Australia2024-08-17 收录
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https://researchdata.edu.au/algorithms-detecting-protein-evaluation-study/1948655
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Since protein complexes play important biological roles in cells, many computational methods have been proposed to detect protein complexes from protein-protein interaction (PPI) data. In this paper, we first review four reputed protein-complex detection algorithms (MCODE[2], MCL[21], CPA[1] and DECAFF[14]) and then present a comprehensive evaluation among them on two popular yeast PPI data3. We also discuss their relative strengthes and disadvantages to guide interested researchers. PRIB 2008 proceedings found at: http://dx.doi.org/10.1007/978-3-540-88436-1 Contributors: Monash University. Faculty of Information Technology. Gippsland School of Information Technology ; Chetty, Madhu ; Ahmad, Shandar ; Ngom, Alioune ; Teng, Shyh Wei ; Third IAPR International Conference on Pattern Recognition in Bioinformatics (PRIB) (3rd : 2008 : Melbourne, Australia) ; Coverage: Rights: Copyright by Third IAPR International Conference on Pattern Recognition in Bioinformatics. All rights reserved.
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Monash University
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