Costs of PEP vaccination regimens from the bite-victim perspective.

Costs were calculated based on whether PEP vaccination is provided free-of-charge, or according to different pricing strategies. The most affordable regimens are emboldened for each strategy. We assume that for each clinic visit patients pay a consultation fee (that is equivalent to the price of overhead for a clinic visit) and the costs of materials for injections (Table 2).1Low indirect costs are assumed to be $2.9/visit (best case scenario in Table 2), corresponding to patients from urban areas that only need to travel relatively short distances to obtain PEP.2High indirect costs are assumed to be $14/visit (worst case scenario in Table 2), which corresponds to patients from rural areas, that have to travel long-distances to a hospital and may need to stay overnight whilst seeking PEP.*For IM regimens, when patients pay for PEP vaccination we assume they pay $10/vial (Table 2).**When using 0.5 mL vials, charging $15 for a full course does not recuperate costs for any ID regimen and charging $10 for each of the first two clinic visits does not recuperate costs for the 1-week ID regimen (see Figure 3).