Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia (expression)

ChEBI2015-09-21 更新2026-07-12 收录

肿瘤靶向治疗

IDH1抑制剂研发

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-72152 数据链接链接失效反馈

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资源简介：

Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia (expression)

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2015-09-21

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药物耐药机制

Protein arginine methyltransferase 5 (PRMT5) over-expression in hematological and solid tumors methylates arginine residues on cellular proteins involved in important cancer functions including cell c

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肿瘤靶分子临床研究信息数据集

肿瘤靶向治疗

临床研究

聚焦肿瘤靶分子临床研究全流程，整合靶点发现、临床试验设计、疗效数据、安全性评估等核心信息。数据经标准化清洗与专业校验，关联靶点分子结构、作用机制及临床结果，支持科研机构靶点验证、药企药物研发、临床机构方案优化，为靶分子临床转化提供高质量、可溯源的数据支撑。

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Regulation of gene expressions in vivo by anti-VEGF and anti-Notch therapy [HG-U133_Plus_2]

肿瘤靶向治疗

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U87-EV human glioblastoma xenograft tumours is therapeutically treated by bevacizumab, a humanized anti-human VEGF mAb, or dibenzazepine (DBZ), when tumour is established in BALB/c SCID mice. At the e

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Novel IDH1 Mutant Inhibitors for Treatment of Acute Myeloid Leukemia (expression)

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