<i>K</i><sub>i</sub> values of the phosphinic compounds H-1 and H-2 for MMP-14, MMP-9(A), MMP-9(MT), ALN, PLN and TLN. The <i><i>K</i></i><sub>i</sub> ± s.d. values were determined for compounds that reduced enzymatic activity by 50% or more at a concentration 100 µM. The s.d. of the <i><i>K</i></i><sub>i</sub> values accounts for the combined s.d. from both the <i>IC</i><sub>50</sub> and <i><i>K</i></i><sub>m</sub> values. The contribution of the <i><i>K</i></i>
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Ki values of the phosphinic compounds H-1 and H-2 for MMP-14, MMP-9(A), MMP-9(MT), ALN, PLN and TLN. The Ki ± s.d. values were determined for compounds that reduced enzymatic activity by 50% or more at a concentration 100 µM. The s.d. of the Ki values accounts for the combined s.d. from both the IC50 and Km values. The contribution of the K
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2025-08-01



