Whole-transcriptome quantitative analysis of WT versus Ikzf4-/- CD4+ T cells cultured in Th1-polarizing conditions
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE147428
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Purpose: To evaluate transcriptome-wide alterations in CD4+ T cells cultured under Th1-polarizing conditions in the absence of the Ikaros zinc finger transcription factor Eos via RNA-seq analysis. Naïve CD4+ T cells (wild type or Ikzf4-/- (Eos KO)) were stimulated on plate-bound anti-CD3 and anti-CD28 in the presence of Th1-polarizing conditions for 72h. Total RNA was analyzed for alterations in global changes to the transcriptome resulting from the absence of the transcription factor Eos.
创建时间：
2020-03-25
