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Spermidine Metabolism Regulates Leukemia Stem and Progenitor Cell Function through KAT7 Expression

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https://www.ncbi.nlm.nih.gov/sra/SRP526030
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To invesetigate the transcriptional changes as a result of polyamine depletion in AML leukemic stem cells and normal hematopoietic stem cells Overall design: Leukemic stem cells enriched from patient samples and hematopoietic sten cells enriched from normal bone marrow samples were treated with polyamine analog DENSpm or control and collected for RNA sequencing.
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2025-01-09
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