Demographic data Study Description This was a phase I, open-label, pharmacokinetic (PK) study with a primary objective of determining PK of sildenafil in premature infants. The trial enrolled 25 prema
To clarify pharmacokinetic-pharmacodynamic (PK-PD) factors associated with the over-anticoagulation response in Asians during warfarin induction therapy, population PK-PD analyses were conducted in a
Percentage of time above the lower and upper range of the EC50/90 and above the EC50/90 means for the different ribavirin regiments based on PK modelling.