Phenotypic resources immortalized in a panel of wild-derived strains of five species of house mice

The house mouse, Mus musculus, is a widely used animal model in biomedical research, with classical laboratory strains (CLS) being the most frequently employed. However, the limited genetic variability in CLS hinders their applicability in evolutionary studies. Wild-derived strains (WDS), on the other hand, provide a suitable resource for such investigations. To assess the proportion of variation added by wild progenitors, we estimated phenotypic variation in 84 WDS representing 5 species (M. musculus, M. spretus, M. spicilegus, M. macedonicus, M. caroli), 3 subspecies (M. m. musculus, M. m. domesticus, M. m. castaneus), and compared it with 5 CLS. The spectrum of WDS captures long-term mouse evolution, estimated to be over 5 million years ago since the split of M. caroli from the remaining mouse species. All mice are housed in a conventional breeding facility (without a nanofilter barrier or specific-pathogen free condition) at the Institute of Vertebrate Biology, Czech Academy of Scie..., The first dataset contains 163 aligned mitogenome sequences. The measures presented in four csv files contaíning phenotype data were obtained from fresh mice immediately after sacrifice, and the units of variables are specified as millimeters (mm) for length measures and grams for mass measures., , # Data from: Phenotypic resources immortalized in a panel of wild-derived strains of five species of house mice

\[[https://doi.org/10.5061/dryad.r7sqv9skn](https://doi.org/10.5061/dryad.r7sqv9skn)]

The dataset comprises five distinct datasets as detailed below:

### Dataset 1: Dataset\_1.Mitogenomes.Aligned.fasta

Contains aligned sequences of 163 whole mitochondrial genomes. The sequences were aligned using Clustal Omega SW (Sievers, Wilm et al. 2011: https://doi.org:10.1038/msb.2011.75 )

### Dataset 2: Morphometric data of male mice

csv file contains raw morphometric data of 2363 male mice with columns:
“Genome” = Taxonomic status of the strain where mus = M. m. musculus, dom = M. m. domesticus, CLS = classical lab strain with predominantly M. m. domesticus genome, cas = M. m. castaneus, car = M. caroli, spi = M. spicilegus, spr = M. spretus, mac = M. macedonicus
“Strain” = wild-derived strain code
“PIN” = identification code of the mouse
“BW” = Body weight (g)
“L” = Body length (...