Structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP and isofagomine analog 2-4

Structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP and isofagomine analog 2-4 Descriptor: (2R,3R,4S,5S)-6-hydrazinyl-2-(hydroxymethyl)-2,3,4,5-tetrahydropyridine-3,4,5-triol, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... Authors: Gilaj, N, Wagner, A.G, Paparella, A.S, Schramm, V.L, Ghosh, A. Deposit date: 2026-01-29 Release date: 2026-07-08 Last modified: 2026-08-05 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Isofagomine Derivatives as TcdB Glucosyltransferase Inhibitors. J.Med.Chem., 69, 2026