Supplementary materials: Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery

These are peer-reviewed supplementary materials for the article 'Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery' published in the Journal of Comparative Effectiveness Research.Search strategy of PubmedSearch strategy of EmbaseSearch strategy of Cochrane librarySearch strategy of CNKIObjective: To evaluate the role of visual pretreatment in preventing emergence delirium in children receiving ophthalmic surgery. Methods: Four randomized controlled trials were identified in four databases, and a meta-analysis was conducted using RevMan 5.3. Results: Themeta-analysis demonstrated a significantly lower incidence of postoperative emergence delirium (risk ratio: 0.39; 95% CI: 0.31–0.49) and propofol rescue (risk ratio: 0.29; 95% CI: 0.13–0.65) but comparable modified Yale Preoperative Anxiety Scale score (mean difference: -3.66; 95% CI: -9.96 to 2.65) and incidence of adverse events in the visual pretreatment group. Conclusion: Visual pretreatment is effective in preventing postoperative emergence delirium in children undergoing ophthalmic surgery without significant adverse effects and can also decrease the incidence of propofol rescue.

本数据集为发表于《比较效果研究杂志》之文章《儿童眼科手术预防术后谵妄的视觉预处理Meta分析》的同行评审补充材料。研究检索策略包括PubMed、Embase、Cochrane图书馆以及CNKI数据库。研究目的在于评估视觉预处理在预防接受眼科手术儿童术后谵妄中的作用。研究方法：在四个数据库中确定了四项随机对照试验，并使用RevMan 5.3软件进行了荟萃分析。研究结果：荟萃分析显示，视觉预处理组术后谵妄发生率显著降低（风险比：0.39；95%置信区间：0.31–0.49），以及丙泊酚抢救发生率显著降低（风险比：0.29；95%置信区间：0.13–0.65），但与视觉预处理组相比，改良耶鲁术前焦虑量表评分（平均差异：-3.66；95%置信区间：-9.96至2.65）和不良事件发生率相当。研究结论：视觉预处理在预防儿童眼科手术术后谵妄方面有效，且未发现显著不良反应，同时也可降低丙泊酚抢救的发生率。