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crystal structure of furanopyrimidine 8 bound to lck

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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crystal structure of furanopyrimidine 8 bound to lck Descriptor: 2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK Authors: Martin, M.W. Deposit date: 2007-01-02 Release date: 2007-02-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties. Bioorg.Med.Chem.Lett., 17, 2007

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2007-01-02
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