相关数据集
Perspective on high-throughput bioanalysis to support in vitro assays in early drug discovery: Supplementary tables
As the desire for a shortened design/make/test/learn cycle increases in early drug discovery, the pressure to rapidly deliver drug metabolism pharmacokinetic data continues to rise. From a bioanalytic
DataCite Commons2024-05-16 更新90
Oral pharmacokinetic interaction of ester rich fruit juices and pharmaceutical excipients with tenofovir disoproxil fumarate in male Wistar rats
1. The aim of this study was to evaluate the role of intestinal esterases on the absorption process of tenofovir disoproxil fumarate (TDF). 2. The esterase inhibition capacity of fruit juices (FJs) ri
Taylor & Francis Group2018-06-21 更新40
Summary of the performance of PCM models.
*Model implemented in Bioclipse Decision Support at www.cyp450model.org.
Figshare2015-12-02 更新30
CEFSULODIN LC/MS/MS DATA
Plasma and brain concentration profiles following IP administration of 100 mg/kg cefsulodin in C57BL/6J mice.
Mendeley Data70
Apparent enzyme kinetic parameters for 4-OH-Cy formation by different microsome batches with recombinant CYP2B6*1 and different POR/CYP ratios.
* POR measured as Cytochrome c reductase activity as in Table 1** Vmax is based on 4-OH-Cy formedCLint Calculated as Vmax/KmCyclophosphamide at different concentrations was incubated in 2 independent
Figshare2015-12-03 更新30
