High-throughput scRNA-seq transcriptionally profiled an estimated 15093 cells from CD islets and 18906 from HFD islets. The mean number of reads per sequenced cell was 43,301 for CD islets and 33,867
Data from E14.5 and E18.5 cohorts were analysed separately by a linear mixed model with maternal STZ and insulin treatment and offspring sex as independent variables, weighted for litter. Values are m
We used streptozotocin-high fat diet (HFD) to induce T2D mouse model, and investigated the effect of standard chow diet and HFD on the composition and function of gut microbiota in them.
Vascular endothelial growth factor-a (VEGF-A) and nitric oxide (NO) are essential for glomerular filtration barrier homeostasis, and are dysregulated in diabetic kidney disease (DKD). While NO availab