Cross reactivity of identified murine T cell epitopes.

The Sequence of reactive peptides identified is given and peptides with homologous sequences within the Ebola and Marburg strains are displayed for comparison. Underlined sequences are the predicted [65] MHC class 1 9mer binding sequence using the ANN algorithm [65], the binding strength to the specific MHC class 1 is given in the last column and was calculated using the T cell epitope prediction tool of the IEDB database (http://www.immuneepitope.org/). Amino acids in bold label the anchoring amino acids of the 9mer according to Rammensee et al. [66].