Extracellular recordings using a dense electrode array allowing direct comparison of the same neural signal measured with low and high impedance electrodes

To help resolve whether the impedance of an electrode matters for recording neural activity with a modern polytrode, we collected a dataset in which neighboring electrodes within a dense array had a 10-fold difference in impedance (PEDOT-coated microelectrodes ~ 100 kΩ and uncoated microelectrodes ~ 1 MΩ). These recordings allow direct comparison of the same neural signal measured with a low and high impedance electrode. Extracellular recordings were obtained from the primary motor cortex (M1) and hippocampus CA1 of ketamine or urethane-anesthetized rats.
Detailed information about the dataset is described in:
Neto, J. P., Baião, P., Lopes, G., Frazão, J., Nogueira, J., Fortunato, E., … Kampff, A. R. (2018). Does impedance matter when recording spikes with polytrodes? Frontiers in Neuroscience, 12, 715. http://doi.org/10.3389/fnins.2018.00715