X-ray Structure of PF-02341066 bound to the kinase domain of c-Met
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X-ray Structure of PF-02341066 bound to the kinase domain of c-Met Descriptor: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, HEPATOCYTE GROWTH FACTOR RECEPTOR Authors: McTigue, M, Grodsky, N, Ryan, K, Tran-Dube, M, Cui, J.J, Mroczkowski, B. Deposit date: 2009-04-20 Release date: 2009-06-02 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure Based Drug Design of Crizotinib (Pf-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal-Epithelial Transition Factor (C-met) Kinase and Anaplastic Lymphoma Kinase (Alk). J.Med.Chem, 54, 2011
创建时间：
2009-04-20
