Dual C–H Functionalization of <i>N</i>‑Aryl Amines: Synthesis of Polycyclic Amines via an Oxidative Povarov Approach
收藏NIAID Data Ecosystem2026-03-09 收录
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资源简介：
Iminium ions generated in situ via copper(I) bromide catalyzed oxidation of N-aryl amines readily undergo [4 + 2] cycloadditions with a range of dienophiles. This method involves the functionalization of both a C(sp3)–H and a C(sp2)–H bond and enables the rapid construction of polycyclic amines under relatively mild conditions.
创建时间：
2015-12-17
