The structure of phosphotyrosine phosphatase 1B in complex with compound 2

The structure of phosphotyrosine phosphatase 1B in complex with compound 2 Descriptor: (4-{(2S,4E)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-[4-(METHOXYCARBONYL)PHENYL]-5-PHENYLPENT-4-ENYL}PHENYL)(DIFLUORO)METHYLPHOSPHONIC ACID, CHLORIDE ION, Tyrosine-protein phosphatase, ... Authors: Asante-Appiah, E, Patel, S, Desponts, C, Taylor, J.M, Lau, C, Dufresne, C, Therien, M, Friesen, R, Becker, J.W, Leblanc, Y, Kennedy, B.P, Scapin, G. Deposit date: 2006-01-03 Release date: 2006-01-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Conformation-assisted inhibition of protein-tyrosine phosphatase-1B elicits inhibitor selectivity over T-cell protein-tyrosine phosphatase. J.Biol.Chem., 281, 2006