One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes
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One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes Descriptor: 1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Gourley, D.G, Hunter, W.N. Deposit date: 2000-09-11 Release date: 2001-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites. Nat.Struct.Biol., 8, 2001
创建时间：
2000-09-11
