Clusters where the SPM analysis showed significant Cues by Gender interaction (Females > Males) for pc>0.05, cluster >200 voxels after covarying for gender differences in daily cocaine use.

The clusters show the location of anatomical region including Brodmann Area (BA) and the coordinates in the Montreal Neurological Institute coordinates x (left to right), y (anterior to posterior) and z (top to bottom), and the corresponding statistical measures at the voxel level (T and Z scores) along with the cluster size for number of voxels. Females showed significantly larger changes in regional metabolism (decreases) than males and there were no brain regions where males had larger changes than females. Note that we report on clusters >45 voxels in order to identify the regions within the large cluster that emerged when we used the preset >200 voxels level.