() ZK cell lines and primary AMs with MSsignificantly diminished phagocytosis of fluorescent latex beads

Wild type primary AMs were used as control. Values shown are the means ± SD from four separate experiments. **Significant difference from WT control, &lt; 0.001. () Polyinosinic acid (PolyI) had no effect but dextran sulfate (DS) increased binding by ZK1 cells. In contrast, PolyI and DS marked reduced wild-type AM binding of the latex beads. Data are expressed as the mean ± SD and compared to the control in each group (WT, MS, ZK1, respectively). *Significant difference compared with ZK1 (&lt; 0.05); **Significant difference compared with WT (&lt; 0.001). PolyI and DS (500 kDa), 10 μg/ml each. () The inhibition of ZK1 cells binding of the latex beads by dextran sulfate was size-dependent. Only smaller 5-8-kDa dextran sulfate was able to inhibit ZK1 cells binding of the latex beads. Data were shown as means ± SD. * &lt; 0.05 versus control (n = 4). DS, 10 μg/ml.<b>Copyright information:</b>Taken from "Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines"http://www.particleandfibretoxicology.com/content/5/1/7Particle and Fibre Toxicology 2008;5():7-7.Published online 2 May 2008PMCID:PMC2427050.