Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab

Cryo-EM structure of SARS-CoV-2 wide-type S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... Authors: Liu, Z.M, Bao, Z.H, Sun, X.Y, Sun, L. Deposit date: 2025-01-06 Release date: 2026-04-22 Last modified: 2026-05-20 Method: ELECTRON MICROSCOPY (6.21 Å) Cite: Steric hindrance of antibody binding in an Omicron spike fusion intermediate. Nature, 2026