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Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma. Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma

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NIAID Data Ecosystem2026-03-12 收录
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The goals of this study are to use multi-omics to design strategies to enhance efficacy of CD38-targeting immunotherapies in myeloma. We compared RNA-seq to cell surface proteomics after genetic and chemical manipulation of CD38 levels in myeloma cell lines. Overall design: Examination of cell surface proteins, phosphoproteins, and RNA levels in myeloma cell lines with different levels of CD38 expression

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2021-08-01
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