Human KRas4A (GDP) in complex with compound 16

Human KRas4A (GDP) in complex with compound 16 Descriptor: 1,2-ETHANEDIOL, 11-(4-aminocyclohexyl)-16-chloro-1,15-dihydroxy-10,10-dioxo-10lambda6-thia-2,11lambda6-diaza-1lambda6,15lambda6-diphospha-3-phosphoniapentacyclo[7.5.1.01,15.03,15.013,15]hexadecan-12-one, GTPase KRas, ... Authors: Schuettelkopf, A.W. Deposit date: 2024-08-14 Release date: 2025-04-16 Last modified: 2025-05-21 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras. J.Med.Chem., 68, 2025