Interleukin-1 induced activation of NF-kB
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Interleukin-1 Induced activation of NF-kB through the phosphorylated TRAF6/Ajuba/PKCz/SQST1 complex. The pathway is defined by multiple binding steps to the TRAF6/Ajuba/PKCz/SQST1 complex. The small arrows constitute a earlier binding. After binding occurs the complex is phosphorylated and activates NF-kB. This pathway is based on figure 6 from Li et al.
白介素-1通过磷酸化的TRAF6/Ajuba/PKCz/SQST1复合物诱导NF-kB的激活。该通路由多个与TRAF6/Ajuba/PKCz/SQST1复合物的结合步骤所定义。细箭头代表早期结合。结合发生后，复合物发生磷酸化并激活NF-kB。此通路基于Li等人的图6。
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