Nucleoprotein translocates to the nucleolus

This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.<br><br>A certain part of the nucleoprotein can be found in the nucleolus. This localisation seems to depend on the protein's sumoylation (Li et al, 2005)

本次COVID-19事件系通过结合对SARS-CoV-1数据的计算推理（参见https://reactome.org/documentation/inferred-events）及人工编纂而成，具体编纂方法详见SARS-CoV-2感染途径概述。某些核蛋白部分可在核仁中发现，其定位似与蛋白质的SUMO化作用（Li等，2005年）密切相关。