CCIDB

To build a database of cellular and tissue contexts, CCIDB collected 38 types of context features, which were categorized into seven categories, including “interaction”, “cell type”, “cofactor”, “effector”, “phenotype”, “pathology”, and “reference”. CCIs were manually retrieved from 272 studies published recently (less than six years ago). In the current version of CCIDB, 520 CCIs and their 38 context features have been manually collected and curated by biodata engineers.为构建细胞与组织上下文数据库，CCIDB 共收集38类上下文特征，并将其划分为七大类别，分别为‘相互作用（interaction）’、‘细胞类型（cell type）’、‘辅助因子（cofactor）’、‘效应因子（effector）’、‘表型（phenotype）’、‘病理学（pathology）’及‘参考（reference）’。研究人员从272项近六年（发表时长不足六年）的已发表研究中手动检索得到细胞间相互作用（Cell-Cell Interactions，CCIs）。在CCIDB当前版本中，生物数据工程师已手动收集并整理注释了520组细胞间相互作用及其对应的38类上下文特征。