Lipid levels and dysfunctional HDL (Dys-HDL) levels at enrollment and 48 hours after enrollment by top quartile SOFA score and SOFA increase over 48 hours.

Student’s T test was performed for HDL-C, LDL-C, and lactate; Wilcoxon’s rank sum test was used for Dys-HDL and ICU stay; and Pearson’s Chi Square test was used for mechanical ventilation and vasopressors use comparisons. HDL, high density lipoprotein. SOFA, sequential organ failure assessment. LDL, low density lipoprotein. HII, HDL inflammatory index. SD, standard deviation. IQR, interquartile range.