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H3K27ac changes upon overexpression of the active NOTCH1 intracellular domain (N1ICD) in human adipose tissue endothelial cells.

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NIAID Data Ecosystem2026-05-01 收录
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The Notch signaling pathway regulates several differentiation and developmental processes, and is involved in the development of a multitude of diseases. Here we investigate by ChIP-Seq the effects of overexpression of the active NOTCH1 intracellular domain (N1ICD) on H3K27ac in human adipose tissue endothelial cells. Overall design: Human adipose tissue endothelial cells were infected with adenoviruses expressing either the active NOTCH1 intracellular domain (N1ICD) or green fluorescent protein (GFP) as a control. Effects on H3K27ac were investigated by ChIP-Seq.

创建时间:
2023-12-09
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