Single cell RNA sequencing analysis of mesenchymal stromal cell-extracellular vesicles treated thymus after neonatal hyperoxia exposure

Using single cell transcriptomics, we aimed at investigating the effects of hyperoxia exposure during the neonatal period on gene expression levels of the various hyperoxia exposed thymus-derived cell populations. In addition, we aimed at investigating how we could modulate neonatal hyperoxia-derived injury of thymus cells by the use of mesenchymal stromal cell-derived extracellular vesicles as potent immunomodulatory therapeutics