Chromatin state changes induced by targeted degradation of MLL-AF9 are phenocopied by combined DOT1L and MENIN inhibition. [SLAM-Seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP317952
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Using SLAM-seq we examined the nascent transcriptional changes following MLL-AF9 degradation in MLL-AF9-HA-FKBP12 transformed hCD34+ cells (HCB1) after 15, 30, 60, and 120 minutes Overall design: Nascent Gene expression changes were assessed in the MLL-AF9-HA-FKBP12 transformed hCD34+ cells (HCB1) following MLL-AF9 degradation after 15, 30, 60, 120 minutes of 500nM dTAG-VHL treatment, compared to DMSO control
创建时间：
2025-07-31
