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Sequential changes of DNA methylation during replicative senescence.

Figshare2017-02-04 更新2026-04-29 收录

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Sequential changes of DNA methylation during replicative senescence.

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2017-02-04

细胞发育表观遗传学

甲基化组学动态分析

A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. Nucleic Acids Res. 2012 Dec;40(22):11339-51.

NIAID Data Ecosystem130

Bulk Omni-ATAC-seq in young (2 months) and aged (22-24 months) mice across 23 cell-types. Bulk Omni-ATAC-seq in young (2 months) and aged (22-24 months) mice across 23 cell-types

衰老表观遗传学

染色质可及性分析

To understand how age rewires the chromatin accessibility landscape, we molecularly profiled 23 purified cell types from 11 tissues and organs by assessing the cumulative signature of 15-25 young and

NIAID Data Ecosystem50

Additional file 6: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

衰老表观遗传学

甲基化数量性状位点

Table S5. Four hundred thirty-six SNPs with genome-wide significant (P < 5 × 10−8) effects on the random slope of 343 rsCpGs. (CSV 27 kb)

NIAID Data Ecosystem40

MeDIP-seq on heart tissues from AMI mouse models

疾病表观遗传学

甲基化组学动态分析

Alterations of DNA methylation modification in heart tissues of AMI mouse models at series of time points (Sham, AMI 10-min, 1-hr, 6-hr, 24-hr and 72-hr)

NIAID Data Ecosystem60

衰老表观遗传学

年龄相关表型甲基化

aPhenotypes are listed as follows: Telomere length, systolic blood pressure (SBP), diastolic blood pressure (DBP), Lung function (FVC), grip strength, bone mineral density (BMD), serum levels of DHEAS

NIAID Data Ecosystem50

Sequential changes of DNA methylation during replicative senescence.

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