Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI

Kappa opioid receptor:Galphai protein in complex with inverse agonist norBNI Descriptor: (4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)-7,12-bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,20,20b-dodecahydro-19aH-4,8:11,15-dimethanobis[1]benzofuro[2,3-a:3',2'-i]dipyrido[4,3-b:3',4'-h]carbazole-1,8a,10a,18-tetrol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Gati, C, Motiwala, Z, Tyson, A.S, Styrpejko, D, Han, G.W, Khan, S, Ramos-Gonzalez, N, Shenvi, R, Majumdar, S. Deposit date: 2024-01-31 Release date: 2025-01-15 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Molecular mechanisms of inverse agonism via kappa-opioid receptor-G protein complexes. Nat.Chem.Biol., 21, 2025