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Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-39 (J1F)

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Protein Data Bank Japan2023-08-30 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6an4
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Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-39 (J1F) Descriptor: ((2-(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carboxamido)-N-(2-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)amino)-2-oxoethyl)acetamido)methyl)phosphonic acid, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION Authors: Shaw, G.X, Shi, G, Ji, X. Deposit date: 2017-08-12 Release date: 2018-08-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Bisubstrate analog inhibitors of HPPK: Transition state mimetics to be published
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2017-08-12
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