Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+
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Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+ Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2023-12-04 Release date: 2024-05-15 Last modified: 2025-06-04 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol eta catalyzed DNA synthesis. J.Biol.Chem., 300, 2024
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2023-12-04
